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Data pro 2019/2020

Retrosynthesis

Kredity 6
Rozsah 3 / 1 / 0
Examinace Zk
Jazyk výuky angličtina
Úroveň []
Garant prof. Ing. Radek Cibulka, Ph.D.

Anotace

None

Sylabus

1. The disconnection approach. Basic principles.
2. Oxidation states of organic compounds.
3. One group C-X disconnections.
4. Two group C-X disconnections.
5. One group C-C disconnections: alcohols.
6. One group C-C disconnections: carbonyl compounds.
7. Alkene and alkyne synthesis.
8. Two group disconnections. 1,3- and 1,5-difunctionalised compounds.
9. Two group disconnections. 1,2-, 1,4- and 1,6-difunctionalised compounds.
10. Strategy of ring synthesis. Baldwin's rules. 3-, 4- and 5-membered rings.
11. Six-membered rings.
12. Heterocycles.
13. Stereoselective synthesis.
14. Linear and convergent synthesis.

Literatura

None

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